How to cite

If you use MitImpact or APOGEE in your research, please cite the relevant works below.

MitImpact

MitImpact 4: a genome-wide resource for the interpretation of coding and non-coding mitochondrial DNA variants

Giovannetti A, Napoli A, Liorni N, Petrizzelli F, Biagini T, Gasbarrini A, Caputo V, Mazza T.

Nucleic Acids Res. 2026 Oct 29; gkag1070.

DOI: 10.1093/nar/gkag1070 · PMID: 42952409

MitImpact 3: modeling the residue interaction network of the Respiratory Chain subunits

Castellana S, Biagini T, Petrizzelli F, Parca L, Panzironi N, Caputo V, Vescovi AL, Carella M, Mazza T.

Nucleic Acids Res. 2021 Jan 8;49(D1):D1282-D1288.

DOI: 10.1093/nar/gkaa1032 · PMID: 33300029

MitImpact: an exhaustive collection of pre-computed pathogenicity predictions of human mitochondrial non-synonymous variants.

Castellana S, Rónai J, Mazza T.

Hum Mutat. 2015 Feb;36(2):E2413-22.

DOI: 10.1002/humu.22720 · PMID: 25516408

APOGEE

APOGEE 2: multi-layer machine-learning model for the interpretable prediction of mitochondrial missense variants

Bianco SD, Parca L, Petrizzelli F, Biagini T, Giovannetti A, Liorni N, Napoli A, Carella M, Procaccio V, Lott MT, Zhang S, Vescovi AL, Wallace DC, Caputo V, Mazza T.

Nat Commun. 2023 Aug 19;14(1):5058

DOI: 10.1038/s41467-023-40797-7 · PMID: 37598215

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Castellana S, Fusilli C, Mazzoccoli G, Biagini T, Capocefalo D, Carella M, Vescovi AL, Mazza T.

PLoS Comput Biol. 2017 Jun 22;13(6):e1005628.

DOI: 10.1371/journal.pcbi.1005628 · PMID: 28640805