About MitImpact

MitImpact is a collection of pre-computed pathogenicity predictions for variants of the human mitochondrial genome. Historically focused on missense (protein-coding) variants, it is being extended to cover tRNA and rRNA variants, each with dedicated, molecule-appropriate features.

Enter a mitochondrial variant in the search box - as a genomic position (3307), a position with allele (3307A>C), an HGVS string (NC_012920.1:g.3307A>C), or a dbSNP rsID (rs199476128) - and MitImpact returns the annotations relevant to that variant's molecule type.